Fibroblast Growth Factor 21 Prevents Atherosclerosis by Suppression of Hepatic Sterol Regulatory Element-Binding Protein-2 and Induction of Adiponectin in Mice

BACKGROUND—: Fibroblast growth factor 21 (FGF21) is a metabolic hormone with pleiotropic effects on glucose and lipid metabolism and insulin sensitivity. It acts as a key downstream target of both peroxisome proliferator-activated receptor α and γ, the agonists of which have been used for lipid lowe...

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Dettagli Bibliografici
Pubblicato in:Circulation
Autori principali: Lin, Zhuofeng, Pan, Xuebo, Wu, Fan, Ye, Dewei, Zhang, Yi, Wang, Yu, Jin, Leigang, Lian, Qizhou, Huang, Yu, Ding, Hong, Triggle, Chris, Wang, Kai, Li, Xiaokun, Xu, Aimin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2015
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444420/
https://ncbi.nlm.nih.gov/pubmed/25794851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.115.015308
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