Pancreatic fibroblast growth factor 21 protects against type 2 diabetes in mice by promoting insulin expression and secretion in a PI3K/Akt signaling‐dependent manner

Fibroblast growth factor 21 (FGF21) is important in glucose, lipid homeostasis and insulin sensitivity. However, it remains unknown whether FGF21 is involved in insulin expression and secretion that are dysregulated in type 2 diabetes mellitus (T2DM). In this study, we found that FGF21 was down‐regu...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Cell Mol Med
Autori principali: Pan, Yingying, Wang, Baile, Zheng, Jujia, Xiong, Rongrong, Fan, Zhichao, Ye, Yanna, Zhang, Saisai, Li, Qinyao, Gong, Fanghua, Wu, Chaoming, Lin, Zhuofeng, Li, Xiaokun, Pan, Xuebo
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
Soggetti:
Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349243/
https://ncbi.nlm.nih.gov/pubmed/30461198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14007
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi