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TCF21 functions as a tumor suppressor in colorectal cancer through inactivation of PI3K/AKT signaling

Colorectal cancer (CRC) has become a major public health problem, ranking as the third most common type of cancer. Our previous study has revealed that TCF21 is frequently silenced by promoter hypermethylation in both CRC cell lines and primary CRC, with TCF21 methylation being significantly correla...

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Bibliografiske detaljer
Udgivet i:Onco Targets Ther
Main Authors: Dai, Youyi, Duan, Huaxin, Duan, Chaojun, Zhu, Hong, Zhou, Rongrong, Pei, Haiping, Shen, Liangfang
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359128/
https://ncbi.nlm.nih.gov/pubmed/28352192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S118151
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