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PTEN Tumor Suppressor Network in PI3K-Akt Pathway Control

The PI3K-Akt pathway is a major survival pathway activated in cancer. Efforts to develop targeted therapies have not been fully successful, mainly because of extensive internal intrapathway or external interpathway negative feedback loops or because of networking between pathway suppressors. The PTE...

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Detalhes bibliográficos
Autor principal: Georgescu, Maria-Magdalena
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092286/
https://ncbi.nlm.nih.gov/pubmed/21779440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911407325
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