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PTEN Tumor Suppressor Network in PI3K-Akt Pathway Control

The PI3K-Akt pathway is a major survival pathway activated in cancer. Efforts to develop targeted therapies have not been fully successful, mainly because of extensive internal intrapathway or external interpathway negative feedback loops or because of networking between pathway suppressors. The PTE...

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Bibliografiske detaljer
Hovedforfatter: Georgescu, Maria-Magdalena
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092286/
https://ncbi.nlm.nih.gov/pubmed/21779440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911407325
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