Combination of aptamer and drug for reversible anticoagulation in cardiopulmonary bypass

Unfractionated heparin (UFH), the standard anticoagulant for cardiopulmonary bypass (CPB) surgery, carries a risk of post-operative bleeding and is potentially harmful in patients with heparin-induced thrombocytopenia-associated antibodies. To improve the activity of an alternative anticoagulant, th...

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Detaylı Bibliyografya
Yayımlandı:Nat Biotechnol
Asıl Yazarlar: Gunaratne, Ruwan, Kumar, Shekhar, Frederiksen, James W., Stayrook, Steven, Lohrmann, Jens L., Perry, Kay, Bompiani, Kristin M., Chabata, Charlene V., Thalji, Nabil K., Ho, Michelle D., Arepally, Gowthami, Camire, Rodney M., Krishnaswamy, Sriram, Sullenger, Bruce A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349032/
https://ncbi.nlm.nih.gov/pubmed/29863725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.4153
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