5‐Oxyacetic Acid Modification Destabilizes Double Helical Stem Structures and Favors Anionic Watson–Crick like cmo(5)U‐G Base Pairs

Watson–Crick like G‐U mismatches with tautomeric G(enol) or U(enol) bases can evade fidelity checkpoints and thereby contribute to translational errors. The 5‐oxyacetic acid uridine (cmo(5)U) modification is a base modification at the wobble position on tRNAs and is presumed to expand the decoding c...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Chemistry
Päätekijät: Strebitzer, Elisabeth, Rangadurai, Atul, Plangger, Raphael, Kremser, Johannes, Juen, Michael Andreas, Tollinger, Martin, Al‐Hashimi, Hashim M., Kreutz, Christoph
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2018
Aiheet:
Communications
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348377/
https://ncbi.nlm.nih.gov/pubmed/30300940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201805077
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