The FXR agonist obeticholic acid inhibits the cancerogenic potential of human cholangiocarcinoma

Cholangiocarcinoma (CCA) is an aggressive cancer with high resistance to chemotherapeutics. CCA is enriched in cancer stem cells, which correlate with aggressiveness and prognosis. FXR, a member of the metabolic nuclear receptor family, is markedly down-regulated in human CCA. Our aim was to evaluat...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Di Matteo, S., Nevi, L., Costantini, D., Overi, D., Carpino, G., Safarikia, S., Giulitti, F., Napoletano, C., Manzi, E., De Rose, A. M., Melandro, F., Bragazzi, M., Berloco, P. B., Giuliante, F., Grazi, G., Giorgi, A., Cardinale, V., Adorini, L., Gaudio, E., Alvaro, D.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345424/
https://ncbi.nlm.nih.gov/pubmed/30677052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210077
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars