Bortezomib sensitizes multiple myeloma to NK cells via ER-stress-induced suppression of HLA-E and upregulation of DR5

Although the proteasome inhibitor bortezomib has significantly improved the survival of patients with multiple myeloma (MM), the disease remains fatal as most patients eventually develop progressive disease. Recent data indicate that MM cells can evade bortezomib-induced cell death by undergoing aut...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Carlsten, Mattias, Namazi, Ali, Reger, Robert, Levy, Emily, Berg, Maria, St. Hilaire, Cynthia, Childs, Richard W.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6343814/
https://ncbi.nlm.nih.gov/pubmed/30713790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1534664
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