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Genetic Manipulation of NK Cells for Cancer Immunotherapy: Techniques and Clinical Implications

Given their rapid and efficient capacity to recognize and kill tumor cells, natural killer (NK) cells represent a unique immune cell to genetically reprogram in an effort to improve the outcome of cell-based cancer immunotherapy. However, technical and biological challenges associated with gene deli...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Carlsten, Mattias, Childs, Richard W.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462109/
https://ncbi.nlm.nih.gov/pubmed/26113846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00266
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