Mechanistic Target of Rapamycin Complex 1 Promotes the Expression of Genes Encoding Electron Transport Chain Proteins and Stimulates Oxidative Phosphorylation in Primary Human Trophoblast Cells by Regulating Mitochondrial Biogenesis

Trophoblast oxidative phosphorylation provides energy for active transport and protein synthesis, which are critical placental functions influencing fetal growth and long-term health. The molecular mechanisms regulating trophoblast mitochondrial oxidative phosphorylation are largely unknown. We hypo...

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Published in:Sci Rep
Main Authors: Rosario, Fredrick J., Gupta, Madhulika B., Myatt, Leslie, Powell, Theresa L., Glenn, Jeremy P., Cox, Laura, Jansson, Thomas
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6343003/
https://ncbi.nlm.nih.gov/pubmed/30670706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36265-8
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