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mTORC1 Transcriptional Regulation of Ribosome Subunits, Protein Synthesis, and Molecular Transport in Primary Human Trophoblast Cells

Mechanistic Target of Rapamycin Complex 1 (mTORC1) serves as positive regulator of placental nutrient transport and mitochondrial respiration. The role of mTORC1 signaling in modulating other placental functions is largely unexplored. We used gene array following silencing of raptor to identify gene...

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Pubblicato in:Front Cell Dev Biol
Autori principali: Rosario, Fredrick J., Powell, Theresa L., Gupta, Madhulika B., Cox, Laura, Jansson, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7726231/
https://ncbi.nlm.nih.gov/pubmed/33324640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.583801
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