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mTORC1 Transcriptional Regulation of Ribosome Subunits, Protein Synthesis, and Molecular Transport in Primary Human Trophoblast Cells

Mechanistic Target of Rapamycin Complex 1 (mTORC1) serves as positive regulator of placental nutrient transport and mitochondrial respiration. The role of mTORC1 signaling in modulating other placental functions is largely unexplored. We used gene array following silencing of raptor to identify gene...

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Detalles Bibliográficos
Publicado en:Front Cell Dev Biol
Main Authors: Rosario, Fredrick J., Powell, Theresa L., Gupta, Madhulika B., Cox, Laura, Jansson, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7726231/
https://ncbi.nlm.nih.gov/pubmed/33324640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.583801
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