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Sirtuin activators and inhibitors: Promises, achievements, and challenges
The NAD(+)-dependent protein lysine deacylases of the Sirtuin family regulate various physiological functions, from energy metabolism to stress responses. The human Sirtuin isoforms, SIRT1-7, are considered attractive therapeutic targets for aging-related diseases, such as type 2 diabetes, inflammat...
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| Publicado no: | Pharmacol Ther |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6342514/ https://ncbi.nlm.nih.gov/pubmed/29577959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2018.03.004 |
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