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A Benzyne Insertion Approach to Hetisine-Type Diterpenoid Alkaloids: Synthesis of Cossonidine (Davisine)

The hetisine-type natural products exhibit one of the most complex carbon skeletons within the diterpenoid alkaloid family. The use of network analysis has enabled a synthesis strategy to access alkaloids in this class with hydroxylation on the A-ring. Key transformations include a benzyne acyl-alky...

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Bibliografiset tiedot
Julkaisussa:J Am Chem Soc
Päätekijät: Kou, Kevin G. M., Pflueger, Jason J., Kiho, Toshihiro, Morrill, Louis C., Fisher, Ethan L., Clagg, Kyle, Lebold, Terry P., Kisunzu, Jessica K., Sarpong, Richmond
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6342194/
https://ncbi.nlm.nih.gov/pubmed/29889509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b05043
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