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Syntheses of Denudatine Diterpenoid Alkaloids: Cochlearenine, N-Ethyl-1α-hydroxy-17-veratroyldictyzine, and Paniculamine

The denudatine-type diterpenoid alkaloids cochlearenine, N-ethyl-1α-hydroxy-17-veratroyldictyzine, and paniculamine have been synthesized for the first time (25, 26, and 26 steps from 16, respectively). These syntheses take advantage of a common intermediate (8) that we have previously employed in p...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Kou, Kevin G. M., Li, Beryl X., Lee, Jack C., Gallego, Gary M., Lebold, Terry P., DiPasquale, Antonio G., Sarpong, Richmond
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076861/
https://ncbi.nlm.nih.gov/pubmed/27525345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b07268
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