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A Case for Bond‐Network Analysis in the Synthesis of Bridged Polycyclic Complex Molecules: Hetidine and Hetisine Diterpenoid Alkaloids

A key challenge in the synthesis of diterpenoid alkaloids lies in identifying strategies that rapidly construct their multiply bridged polycyclic skeletons. Existing approaches to these structurally intricate secondary metabolites are discussed in the context of a “bond‐network analysis” of molecula...

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Pubblicato in:Angew Chem Int Ed Engl
Autori principali: Doering, Nicolle A., Sarpong, Richmond, Hoffmann, Reinhard W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7317470/
https://ncbi.nlm.nih.gov/pubmed/31808282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201909656
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