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Duocarmycin SA, a potent antitumor antibiotic, sensitizes glioblastoma cells to proton radiation

New treatment modalities for glioblastoma multiforme (GBM) are urgently needed. Proton therapy is considered one of the most effective forms of radiation therapy for GBM. DNA alkylating agents such as temozolomide (TMZ) are known to increase the radiosensitivity of GBM to photon radiation. TMZ is a...

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Dades bibliogràfiques
Publicat a:Bioorg Med Chem Lett
Autors principals: Boyle, Kristopher E., Boger, Dale L., Wroe, Andrew, Vazquez, Marcelo
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6339562/
https://ncbi.nlm.nih.gov/pubmed/29650288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2018.04.008
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