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Duocarmycin SA, a potent antitumor antibiotic, sensitizes glioblastoma cells to proton radiation

New treatment modalities for glioblastoma multiforme (GBM) are urgently needed. Proton therapy is considered one of the most effective forms of radiation therapy for GBM. DNA alkylating agents such as temozolomide (TMZ) are known to increase the radiosensitivity of GBM to photon radiation. TMZ is a...

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Bibliografiske detaljer
Udgivet i:Bioorg Med Chem Lett
Main Authors: Boyle, Kristopher E., Boger, Dale L., Wroe, Andrew, Vazquez, Marcelo
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6339562/
https://ncbi.nlm.nih.gov/pubmed/29650288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2018.04.008
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