Chronic ethanol-mediated hepatocyte apoptosis links to decreased TET1 and 5-hydroxymethylcytosine formation

The 5-hydroxymethylcytosine (5hmc) is a newly identified epigenetic modification thought to be regulated by the TET family of proteins. Little information is available about how ethanol consumption may modulate 5hmC formation and alcoholic liver disease (ALD) progression. A rat ALD model was used to...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Ji, Chengcheng, Nagaoka, Katsuya, Zou, Jing, Casulli, Sarah, Lu, Shaolei, Cao, Kevin Y., Zhang, Hongyu, Iwagami, Yoshifumi, Carlson, Rolf I., Brooks, Keri, Lawrence, Jonathan, Mueller, William, Wands, Jack R., Huang, Chiung-Kuei
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338639/
https://ncbi.nlm.nih.gov/pubmed/30188753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201800736R
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