Chronic ethanol-mediated hepatocyte apoptosis links to decreased TET1 and 5-hydroxymethylcytosine formation

The 5-hydroxymethylcytosine (5hmc) is a newly identified epigenetic modification thought to be regulated by the TET family of proteins. Little information is available about how ethanol consumption may modulate 5hmC formation and alcoholic liver disease (ALD) progression. A rat ALD model was used to...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:FASEB J
Hauptverfasser: Ji, Chengcheng, Nagaoka, Katsuya, Zou, Jing, Casulli, Sarah, Lu, Shaolei, Cao, Kevin Y., Zhang, Hongyu, Iwagami, Yoshifumi, Carlson, Rolf I., Brooks, Keri, Lawrence, Jonathan, Mueller, William, Wands, Jack R., Huang, Chiung-Kuei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2019
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6338639/
https://ncbi.nlm.nih.gov/pubmed/30188753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201800736R
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge