TET family proteins and 5-hydroxymethylcytosine in esophageal squamous cell carcinoma

Mammalian DNA is epigenetically marked by 5′-cytosine methylation (5-methylcytosine [5-mC]). The Ten-eleven translocation (TET) enzymes (TET1, TET2, and TET3) are implicated in DNA demethylation, through dioxygenase activity that converts 5-mC to 5-hydroxymethylcytosine (5-hmC). Although decreased T...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Murata, Asuka, Baba, Yoshifumi, Ishimoto, Takatsugu, Miyake, Keisuke, Kosumi, Keisuke, Harada, Kazuto, Kurashige, Junji, Iwagami, Shiro, Sakamoto, Yasuo, Miyamoto, Yuji, Yoshida, Naoya, Yamamoto, Manabu, Oda, Shinya, Watanabe, Masayuki, Nakao, Mitsuyoshi, Baba, Hideo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695124/
https://ncbi.nlm.nih.gov/pubmed/26093090
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