UHRF1 regulates global DNA hypomethylation and is associated with poor prognosis in esophageal squamous cell carcinoma

BACKGROUND: Global DNA hypomethylation contributes to oncogenesis through various mechanisms. The level of long interspersed nucleotide element-1 (LINE- 1) methylation is considered a surrogate marker of global DNA methylation, and is attracting interest as a good predictor of cancer prognosis. Howe...

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Pubblicato in:Oncotarget
Autori principali: Nakamura, Kenichi, Baba, Yoshifumi, Kosumi, Keisuke, Harada, Kazuto, Shigaki, Hironobu, Miyake, Keisuke, Kiyozumi, Yuki, Ohuchi, Mayuko, Kurashige, Junji, Ishimoto, Takatsugu, Iwatsuki, Masaaki, Sakamoto, Yasuo, Yoshida, Naoya, Watanabe, Masayuki, Nakao, Mitsuyoshi, Baba, Hideo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5295392/
https://ncbi.nlm.nih.gov/pubmed/27507047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11067
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