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TET1 promotes malignant progression of cholangiocarcinoma with IDH1 wild-type
Cholangiocarcinoma (CCA) is a highly lethal disease without effective therapeutic approaches. The whole genome sequencing data indicated that there are about 20% of CCA patients having IDH1 mutations which have been suggested to target 2-oxoglutarate (OG) dependent dioxygenases in promoting CCA carc...
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| Udgivet i: | Hepatology |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7855500/ https://ncbi.nlm.nih.gov/pubmed/32740973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.31486 |
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