TET1 promotes malignant progression of cholangiocarcinoma with IDH1 wild-type

Cholangiocarcinoma (CCA) is a highly lethal disease without effective therapeutic approaches. The whole genome sequencing data indicated that there are about 20% of CCA patients having IDH1 mutations which have been suggested to target 2-oxoglutarate (OG) dependent dioxygenases in promoting CCA carc...

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Pubblicato in:Hepatology
Autori principali: Bai, Xuewei, Zhang, Hongyu, Zhou, Yamei, Nagaoka, Katsuya, Meng, Jialin, Ji, Chengcheng, Liu, Dan, Dong, Xianghui, Cao, Kevin, Mulla, Joud, Cheng, Zhixiang, Mueller, William, Bay, Amalia, Hildebrand, Grace, Lu, Shaolei, Wallace, Joselynn, Wands, Jack R., Sun, Bei, Huang, Chiung-Kuei
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855500/
https://ncbi.nlm.nih.gov/pubmed/32740973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.31486
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