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Tip60- and sirtuin 2-regulated MARCKS acetylation and phosphorylation are required for diabetic embryopathy

Failure of neural tube closure results in severe birth defects and can be induced by high glucose levels resulting from maternal diabetes. MARCKS is required for neural tube closure, but the regulation and of its biological activity and function have remained elusive. Here, we show that high materna...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Yang, Penghua, Xu, Cheng, Reece, E. Albert, Chen, Xi, Zhong, Jianxiang, Zhan, Min, Stumpo, Deborah J., Blackshear, Perry J., Yang, Peixin
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336777/
https://ncbi.nlm.nih.gov/pubmed/30655546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-08268-6
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