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The increased activity of a transcription factor inhibits autophagy in diabetic embryopathy

BACKGROUND: Maternal diabetes induces neural tube defects and stimulates the activity of the forkhead box O3 (Fox)O3a in the embryonic neuroepithelium. We previously demonstrated that deleting the FOXO3a gene ameliorates maternal diabetes-induced neural tube defects. Macroautophagy (hereafter referr...

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Bibliographic Details
Published in:Am J Obstet Gynecol
Main Authors: Xu, Cheng, Chen, Xi, Reece, E. Albert, Lu, Wenhui, Yang, Peixin
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463484/
https://ncbi.nlm.nih.gov/pubmed/30312583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2018.10.001
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