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The increased activity of a transcription factor inhibits autophagy in diabetic embryopathy

BACKGROUND: Maternal diabetes induces neural tube defects and stimulates the activity of the forkhead box O3 (Fox)O3a in the embryonic neuroepithelium. We previously demonstrated that deleting the FOXO3a gene ameliorates maternal diabetes-induced neural tube defects. Macroautophagy (hereafter referr...

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Bibliografiske detaljer
Udgivet i:Am J Obstet Gynecol
Main Authors: Xu, Cheng, Chen, Xi, Reece, E. Albert, Lu, Wenhui, Yang, Peixin
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463484/
https://ncbi.nlm.nih.gov/pubmed/30312583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2018.10.001
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