Superoxide dismutase 1 overexpression in mice abolishes maternal diabetes—induced endoplasmic reticulum stress in diabetic embryopathy

OBJECTIVE: Both oxidative stress and endoplasmic reticulum stress (ER stress) are causal events in diabetic embryopathy. We tested whether oxidative stress causes ER stress. STUDY DESIGN: Wild-type (WT) and superoxide dismutase 1 (SOD1)—overexpressing day 8.75 embryos from nondiabetic WT control wit...

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Bibliographic Details
Main Authors: Wang, Fang, Reece, E. Albert, Yang, Peixin
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786037/
https://ncbi.nlm.nih.gov/pubmed/23791840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2013.06.037
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