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Reduction in Embryonic Malformations and Alleviation of Endoplasmic Reticulum Stress by Nitric Oxide Synthase Inhibition in Diabetic Embryopathy

Maternal diabetes-induced neural tube defects (NTDs) are associated with increased programmed cell death (apoptosis) in the neuroepithelium, which is related to intracellular nitrosative stress. To alleviate nitrosative stress, diabetic pregnant mice were fed via gavage an inhibitor of nitric oxide...

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Detalhes bibliográficos
Main Authors: Zhao, Zhiyong, Eckert, Richard L., Reece, E. Albert
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046311/
https://ncbi.nlm.nih.gov/pubmed/22534324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1933719111434543
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