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GREB1 amplifies androgen receptor output in human prostate cancer and contributes to antiandrogen resistance
Genomic amplification of the androgen receptor (AR) is an established mechanism of antiandrogen resistance in prostate cancer. Here, we show that the magnitude of AR signaling output, independent of AR genomic alteration or expression level, also contributes to antiandrogen resistance, through upreg...
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| 出版年: | eLife |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6336405/ https://ncbi.nlm.nih.gov/pubmed/30644358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41913 |
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