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Conserved function of the matriptase-prostasin proteolytic cascade during epithelial morphogenesis

Extracellular matrix (ECM) assembly and remodelling is critical during development and organ morphogenesis. Dysregulation of ECM is implicated in many pathogenic conditions, including cancer. The type II transmembrane serine protease matriptase and the serine protease prostasin are key factors in a...

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Bibliografiske detaljer
Udgivet i:PLoS Genet
Main Authors: Drees, Leonard, Königsmann, Tatiana, Jaspers, Martin H. J., Pflanz, Ralf, Riedel, Dietmar, Schuh, Reinhard
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331135/
https://ncbi.nlm.nih.gov/pubmed/30601807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007882
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