Regulation of the Matriptase-Prostasin Cell Surface Proteolytic Cascade by Hepatocyte Growth Factor Activator Inhibitor-1 during Epidermal Differentiation

Matriptase, a membrane-tethered serine protease, plays essential roles in epidermal differentiation and barrier function, largely mediated via its activation of prostasin, a glycosylphosphatidylinositol-anchored serine protease. Matriptase activity is tightly regulated by its inhibitor hepatocyte gr...

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Detalhes bibliográficos
Main Authors: Chen(陳, Ya-Wen, 亞雯), Wang(王, Jehng-Kang, 正康), Chou(周, Feng-Pai, 封百), Chen(陳, Chiu-Yuan, 秋媛), Rorke, Ellen A., Chen, Li-Mei, Chai, Karl X., Eckert, Richard L., Johnson, Michael D., Lin(林, Chen-Yong, 陳鏞)
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951247/
https://ncbi.nlm.nih.gov/pubmed/20696767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.150367
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