In vivo and Cellular Trafficking of Acetalated Dextran Microparticles for Delivery of a Host-Directed Therapy for Salmonella enterica Serovar Typhi Infection

Previously we have encapsulated host-directed therapy AR-12 into acetalated dextran (Ace-DEX) microparticles (MPs) to mitigate drug toxicity and passively target phagocytic host cells. Herein, we have improved upon our initial emulsion-based formulation of Ace-DEX MPs encapsulating AR-12 (AR-12/MPs)...

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Vydáno v:Mol Pharm
Hlavní autoři: Johnson, Monica M., Collier, Michael A., Hoang, Ky V., Pino, Erica N., Gurysh, Elizabeth G., Gallovic, Matthew D., Zahid, Md. Shamim Hasan, Chen, Naihan, Schlesinger, Larry S., Gunn, John S., Bachelder, Eric M., Ainslie, Kristy M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330710/
https://ncbi.nlm.nih.gov/pubmed/30296381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.8b00802
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