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Needle-Free Delivery of Acetalated Dextran-Encapsulated AR-12 Protects Mice from Francisella tularensis Lethal Challenge

Francisella tularensis causes tularemia and is a potential biothreat. Given the limited antibiotics for treating tularemia and the possible use of antibiotic-resistant strains as a biowarfare agent, new antibacterial agents are needed. AR-12 is an FDA-approved investigational new drug (IND) compound...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Antimicrob Agents Chemother
मुख्य लेखकों: Hoang, Ky V., Curry, Heather, Collier, Michael A., Borteh, Hassan, Bachelder, Eric M., Schlesinger, Larry S., Gunn, John S., Ainslie, Kristy M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808193/
https://ncbi.nlm.nih.gov/pubmed/26787696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02228-15
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