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Tunable Degradation of Acetalated Dextran Microparticles Enables Controlled Vaccine Adjuvant and Antigen Delivery to Modulate Adaptive Immune Responses

Subunit vaccines are often poorly immunogenic, and adjuvants and/or delivery vehicles, such as polymeric microparticles (MPs), can be used to enhance immune responses. MPs can also be used to understand cell activation kinetics and the significant impact antigen and adjuvant release has on adaptive...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Chen, Naihan, Johnson, Monica M., Collier, Michael A., Gallovic, Matthew D., Bachelder, Eric M., Ainslie, Kristy M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835201/
https://ncbi.nlm.nih.gov/pubmed/29407676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.01.027
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