In vitro analysis of acetalated dextran microparticles as a potent delivery platform for vaccine adjuvants

Toll-like receptor (TLR) agonists induce potent innate immune responses and can be used in the development of novel vaccine adjuvants. However, access to TLRs can be challenging as exemplified by TLR 7, which is located intracellularly in endosomal compartments. To increase recognition and subsequen...

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Huvudupphovsmän: Bachelder, Eric M., Beaudette, Tristan T., Broaders, Kyle E., Fréchet, Jean MJ., Albrecht, Mark T., Mateczun, Alfred J., Ainslie, Kristy M., Pesce, John T., Keane-Myers, Andrea M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882515/
https://ncbi.nlm.nih.gov/pubmed/20230025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp900311x
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