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Tunable Degradation of Acetalated Dextran Microparticles Enables Controlled Vaccine Adjuvant and Antigen Delivery to Modulate Adaptive Immune Responses

Subunit vaccines are often poorly immunogenic, and adjuvants and/or delivery vehicles, such as polymeric microparticles (MPs), can be used to enhance immune responses. MPs can also be used to understand cell activation kinetics and the significant impact antigen and adjuvant release has on adaptive...

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Dades bibliogràfiques
Publicat a:J Control Release
Autors principals: Chen, Naihan, Johnson, Monica M., Collier, Michael A., Gallovic, Matthew D., Bachelder, Eric M., Ainslie, Kristy M.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835201/
https://ncbi.nlm.nih.gov/pubmed/29407676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.01.027
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