COPI-Mediated Nuclear Translocation of EGFRvIII Promotes STAT3 Phosphorylation and PKM2 Nuclear Localization

As a non-ligand-dependent activation protein, EGFRvIII is the most common mutant of EGFR, and its existence or especially its nuclear translocation in tumors can exacerbate the malignancy. Compared with the nuclear translocation of EGFR, which has been studied extensively, the specific mechanism by...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Int J Biol Sci
Egile Nagusiak: Zhang, Mingzhi, Sun, Haojie, Deng, Yue, Su, Ming, Wei, Shiruo, Wang, Peipei, Yu, Lanlan, Liu, Jinwen, Guo, Jinhai, Wang, Xuan, Han, Xu, He, Qihua, Shen, Li
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Ivyspring International Publisher 2019
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329918/
https://ncbi.nlm.nih.gov/pubmed/30662352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.28679
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