Ex vivo culture of cells derived from circulating tumour cell xenograft to support small cell lung cancer research and experimental therapeutics

BACKGROUND AND PURPOSE: Small cell lung cancer (SCLC) is an aggressive disease with median survival of <2 years. Tumour biopsies for research are scarce, especially from extensive‐stage patients, with repeat sampling at disease progression rarely performed. We overcame this limitation for relevan...

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Udgivet i:Br J Pharmacol
Main Authors: Lallo, Alice, Gulati, Sakshi, Schenk, Maximilian W, Khandelwal, Garima, Berglund, Ulrika Warpman, Pateras, Ioannis S, Chester, Christopher P E, Pham, Therese M, Kalderen, Christina, Frese, Kristopher K, Gorgoulis, Vassilis G, Miller, Crispin, Blackhall, Fiona, Helleday, Thomas, Dive, Caroline
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329630/
https://ncbi.nlm.nih.gov/pubmed/30427531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14542
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