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Mutations in Cancer Cause Gain of Cysteine, Histidine, and Tryptophan at the Expense of a Net Loss of Arginine on the Proteome Level

Accumulation of somatic mutations is critical for the transition of a normal cell to become cancerous. Mutations cause amino acid substitutions that change properties of proteins. However, it has not been studied as to what extent the composition and accordingly chemical properties of the cell prote...

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Vydáno v:Biomolecules
Hlavní autoři: Tsuber, Viktoriia, Kadamov, Yunus, Brautigam, Lars, Warpman Berglund, Ulrika, Helleday, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618230/
https://ncbi.nlm.nih.gov/pubmed/28671612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom7030049
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