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Mutations in Cancer Cause Gain of Cysteine, Histidine, and Tryptophan at the Expense of a Net Loss of Arginine on the Proteome Level

Accumulation of somatic mutations is critical for the transition of a normal cell to become cancerous. Mutations cause amino acid substitutions that change properties of proteins. However, it has not been studied as to what extent the composition and accordingly chemical properties of the cell prote...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Tsuber, Viktoriia, Kadamov, Yunus, Brautigam, Lars, Warpman Berglund, Ulrika, Helleday, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618230/
https://ncbi.nlm.nih.gov/pubmed/28671612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom7030049
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