Glioblastoma and glioblastoma stem cells are dependent on functional MTH1

Glioblastoma multiforme (GBM) is an aggressive form of brain cancer with poor prognosis. Cancer cells are characterized by a specific redox environment that adjusts metabolism to its specific needs and allows the tumor to grow and metastasize. As a consequence, cancer cells and especially GBM cells...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Pudelko, Linda, Rouhi, Pegah, Sanjiv, Kumar, Gad, Helge, Kalderén, Christina, Höglund, Andreas, Squatrito, Massimo, Schuhmacher, Alberto J., Edwards, Steven, Hägerstrand, Daniel, Berglund, Ulrika Warpman, Helleday, Thomas, Bräutigam, Lars
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2017
Assuntos:
Priority Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5689565/
https://ncbi.nlm.nih.gov/pubmed/29156675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19404
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