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Statistical investigations of protein residue direct couplings

Protein Direct Coupling Analysis (DCA), which predicts residue-residue contacts based on covarying positions within a multiple sequence alignment, has been remarkably effective. This suggests that there is more to learn from sequence correlations than is generally assumed, and calls for deeper inves...

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Bibliografske podrobnosti
izdano v:PLoS Comput Biol
Main Authors: Neuwald, Andrew F., Altschul, Stephen F.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329532/
https://ncbi.nlm.nih.gov/pubmed/30596639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006237
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