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Histone demethylase KDM6B has an anti-tumorigenic function in neuroblastoma by promoting differentiation
Induction of differentiation is a therapeutic strategy in high-risk neuroblastoma, a childhood cancer of the sympathetic nervous system. Neuroblastoma differentiation requires transcriptional upregulation of neuronal genes. How this process is regulated at epigenetic levels is not well understood. H...
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| 發表在: | Oncogenesis |
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| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6328563/ https://ncbi.nlm.nih.gov/pubmed/30631055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-018-0112-0 |
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