Načítá se...
Structure-guided design of anti-cancer ribonucleotide reductase inhibitors
Ribonucleotide reductase (RR) catalyses the rate-limiting step of dNTP synthesis, establishing it as an important cancer target. While RR is traditionally inhibited by nucleoside-based antimetabolites, we recently discovered a naphthyl salicyl acyl hydrazone-based inhibitor (NSAH) that binds reversi...
Uloženo v:
| Vydáno v: | J Enzyme Inhib Med Chem |
|---|---|
| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
2019
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6328008/ https://ncbi.nlm.nih.gov/pubmed/30734609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1545226 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|