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Triazole-linked transition state analogs as selective inhibitors against V. cholera sialidase
Sialidases or neuraminidases are enzymes that catalyze the cleavage of terminal sialic acids from oligosaccharides and glycoconjugates. They play important roles in bacterial and viral infection and have been attractive targets for drug development. Structure-based drug design has led to potent inhi...
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| Publicado no: | Bioorg Med Chem |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6326775/ https://ncbi.nlm.nih.gov/pubmed/30389408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2018.10.028 |
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