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Chemoenzymatic synthesis of sialosides containing C7-modified sialic acids and their application in sialidase substrate specificity studies

Modification at the glycerol side chain of sialic acid in sialosides modulate their recognition by sialic acid-binding proteins and sialidases. However, limited work has been focused on the synthesis and functional studies of sialosides with C7-modified sialic acids. Here we report chemical synthesi...

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Detalhes bibliográficos
Main Authors: Khedri, Zahra, Li, Yanhong, Muthana, Saddam, Muthana, Musleh M., Hsiao, Ching-Wen, Yu, Hai, Chen, Xi
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074090/
https://ncbi.nlm.nih.gov/pubmed/24680514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2014.02.021
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