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Chemoenzymatic synthesis of para-nitrophenol (pNP)-tagged α2–8-sialosides and high-throughput substrate specificity studies of α2–8-sialidases()

para-Nitrophenol (pNP)-tagged α2–8-linked sialosides containing different sialic acid forms were chemoenzymatically synthesized using an efficient one-pot three-enzyme α2–8-sialylation system. The resulting compounds allowed high-throughput substrate specificity studies of the α2–8-sialidase activit...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Tasnima, Nova, Yu, Hai, Li, Yanhong, Santra, Abhishek, Chen, Xi
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173422/
https://ncbi.nlm.nih.gov/pubmed/27924345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6ob02240e
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