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Common and Potentially Prebiotic Origin for Precursors of Nucleotide Synthesis and Activation
[Image: see text] We have recently shown that 2-aminoimidazole is a superior nucleotide activating group for nonenzymatic RNA copying. Here we describe a prebiotic synthesis of 2-aminoimidazole that shares a common mechanistic pathway with that of 2-aminooxazole, a previously described key intermedi...
Enregistré dans:
| Publié dans: | J Am Chem Soc |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Chemical
Society
2017
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6326526/ https://ncbi.nlm.nih.gov/pubmed/28640999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b01562 |
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