Enhanced Nonenzymatic RNA Copying with 2-Aminoimidazole Activated Nucleotides

[Image: see text] Achieving efficient nonenzymatic replication of RNA is an important step toward the synthesis of self-replicating protocells that may mimic early forms of life. Despite recent progress, the nonenzymatic copying of templates containing mixed sequences remains slow and inefficient. H...

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Publicado en:J Am Chem Soc
Main Authors: Li, Li, Prywes, Noam, Tam, Chun Pong, O’Flaherty, Derek K., Lelyveld, Victor S., Izgu, Enver Cagri, Pal, Ayan, Szostak, Jack W.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2017
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326525/
https://ncbi.nlm.nih.gov/pubmed/28117989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b13148
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