Synergistic antitumor effects of 9.2.27-PE38KDEL and ABT-737 in primary and metastatic brain tumors

Standard treatment, unfortunately, yields a poor prognosis for patients with primary or metastatic cancers in the central nervous system, indicating a necessity for novel therapeutic agents. Immunotoxins (ITs) are a class of promising therapeutic candidates produced by fusing antibody fragments with...

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Vydáno v:PLoS One
Hlavní autoři: Yu, Xin, Dobrikov, Mikhail, Keir, Stephen T., Gromeier, Matthias, Pastan, Ira H., Reisfeld, Ralph, Bigner, Darell D., Chandramohan, Vidyalakshmi
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326518/
https://ncbi.nlm.nih.gov/pubmed/30625226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210608
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