Pathway-Directed Screen for Inhibitors of the Bacterial Cell Elongation Machinery

New antibiotics are needed to combat the growing problem of resistant bacterial infections. An attractive avenue toward the discovery of such next-generation therapies is to identify novel inhibitors of clinically validated targets, like cell wall biogenesis. We have therefore developed a pathway-di...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Buss, Jackson A., Baidin, Vadim, Welsh, Michael A., Flores-Kim, Josué, Cho, Hongbaek, Wood, B. McKay, Uehara, Tsuyoshi, Walker, Suzanne, Kahne, Daniel, Bernhardt, Thomas G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2018
Matèries:
Mechanisms of Action: Physiological Effects
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325226/
https://ncbi.nlm.nih.gov/pubmed/30323039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01530-18
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